The analgesic activity of tramadol hydrochloride is due to both mum or dad drug and also the M1 metabolite (seeCLINICAL PHARMACOLOGY, Pharmacodynamics). Tramadol is administered for a racemate and the two the [-] and [+] sorts of both tramadol and M1 are detected while in the circulation. Tramadol is properly absorbed orally having an absolute bioa